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How GASTROGARD® (omeprazole) works

A horse’s stomach is relatively small and cannot handle large amounts of feed — so it must eat frequent, small portions of feed. It produces acid throughout the entire day.1


When roughage intake is interrupted acidity increases, which can lead to ulceration, or eating away at the stomach’s protective lining. By reducing appetite, this starts a vicious cycle of pain and suffering for your horse.2


Diagram

GASTROGARD breaks the cycle at the acid pump

Unlike antacids and other products being marketed without FDA approval for treating equine stomach ulcers, GASTROGARD stops stomach acid production at its source — by inhibiting the acid pump.3


This allows GASTROGARD to provide superior treatment and healing of equine stomach ulcers4 — because its mode of action blocks acid secretion, regardless of the stimulus.5



Important safety information:


CAUTION: Safety of GASTROGARD in pregnant or lactating mares has not been determined.

For prescription information for GASTROGARD, click here.


®GASTROGARD is a registered trademark of the AstraZeneca Group of Companies.


1Kitchen DL, Merritt AM, Burrow JA. Histamine-induced gastric acid secretion in horses. AJVR 1998;59(10):1303-1306.

2Murray MJ. Disorders of the stomach. In: Smith BP, ed. Large Animal Internal Medicine. St. Louis; CV Mosby, 1990;710-717.

3Equine Gastric Ulcer Council. Recommendations for the diagnosis and treatment of Equine Gasgric Ulcer Syndrome (EGUS). Equine Vet Educ 1999;11:262-272.

4Freedom of Information (FOI) Summary for GASTROGARD Oral Paste for Horses.

5Nieto, JE, et al. Comparison of omeprazole and cimetidine in healing of gastric ulcers and prevention of recurrence in horses. Equine Vet Educ 2001;18:260-264.

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Photography by David R. Stoecklein

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